Description
A member of the class of 2,6-diaminopurines that is 9H-purine in which the hydrogens at positions 2 and 6 are replaced by amino groups.
Chemical properties
| Chemical formula | Net charge | Average mass |
|---|---|---|
| C5H6N6 | 0 | 150.14130 |
Recommended notation
| Name | 2-aminoadenine |
|---|---|
| Abbreviation | m2A |
Nomenclature
| SMILES | InChI | InChIKey | Synonyms |
|---|---|---|---|
| Nc1nc(N)c2nc[nH]c2n1 | InChI=1S/C5H6N6/c6-3-2-4(9-1-8-2)11-5(7)10-3/h1H,(H5,6,7,8,9,10,11) | MSSXOMSJDRHRMC-UHFFFAOYSA-N |
|
Nature
| Origin | Function | Functional detail |
Organisms
|
References |
|---|---|---|---|---|
| natural | hypermodified nucleobase | Cyanophage S-2L |
|
Citations
- González-Pérez, JM, et al. 2015. Molecular recognition between adenine or 2,6-diaminopurine and copper(II) chelates with N,O2,S-tripodal tetradentate chelators having thioether or disulfide donor groups. Journal of Inorganic Biochemistry. 151.
- Khudyakov, IY, et al. 1978. Cyanophage S-2L contains DNA with 2,6-diaminopurine substituted for adenine. Virology. 88(1).
- Kirnos, MD, et al. 1977. 2-aminoadenine is an adenine substituting for a base in S-2L cyanophage DNA. Nature. 270(5635).
- Sági, J, et al. 1996. Unusual contribution of 2-aminoadenine to the thermostability of DNA. Journal of Biomolecular Structure & Dynamics. 13(6).